Protein frequency isomers
Laboratory of Systems Technology for Disease Program Management ™
Selected fragments of the 4th edition of the book: Prolegomena to Future Metamedicine. Part I. 2019. Author: MD, PhD, Professor V. Revo
Protein frequency isomers (V. Revo, 2008) – is the definition of a specific form of the living being first level of systemic organization (I LSO), in which the secondary structure of the normal soluble PrPC protein can undergo a phase transition into the PrPSc form. Since the conformational dynamics (hydration ⇄ dehydration) is manifested in the secondary structure of the protein, it is possible to draw an analogy with isomerization. Protein isomers differ from the original forms by the intrinsic frequency of conformational dynamics; therefore, they should be represented as protein frequency isomers. This is of great practical importance for diagnosis. ….
For details, see Prion in my book Prolegomena to Future Metamedicine. Part II.
© Valeriy Revo 2019
Laboratory of Systems Technology for Disease Program Management ™
Selected fragments of the 4th edition of the book: Prolegomena to Future Metamedicine. Part I. 2019. Author: MD, PhD, Professor V. Revo
Protein frequency isomers (V. Revo, 2008) – is the definition of a specific form of the living being first level of systemic organization (I LSO), in which the secondary structure of the normal soluble PrPC protein can undergo a phase transition into the PrPSc form. Since the conformational dynamics (hydration ⇄ dehydration) is manifested in the secondary structure of the protein, it is possible to draw an analogy with isomerization. Protein isomers differ from the original forms by the intrinsic frequency of conformational dynamics; therefore, they should be represented as protein frequency isomers. This is of great practical importance for diagnosis. ….
For details, see Prion in my book Prolegomena to Future Metamedicine. Part II.
© Valeriy Revo 2019
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