Disease and Illness
Laboratory of Disease Program Management Technologies™
Selected fragments of the 4th edition of the book of MD, PhD, Professor V. Revo "Prolegomena to Future Metamedicine." Part I. 2019.
Disease, syn. Nosological form – is the definition of the phenomenon of unfolding in the body of a phylogenetically determined innate specific program process, which reduce the adaptive capabilities of a living being. However, today the disease is presented as "… any harmful deviation from the normal structural or functional state of the body, usually associated with certain signs and symptoms and differing in nature from physical damage" [62]. The epithet "harmful" is not correct in this context, because in the body we have various forms of harmfulness, e.g., many metabolic products. The World Health Organization defines the disease as "a violation of the function or structure of any part of the body" due to the inability to fully adapt to "stimuli and stresses." It is assumed that the disease "can be prevented or treated by changing any combination of factors" [63]. These declarations illustrate the archaic nature-philosophical approach to the disease, which cannot offer technologies for the prevention of non-communicable diseases by definition. The systemic information paradigm (V. Revo, 1986) represents the disease as a phased development in the organism of any particular phylogenetically conditioned congenital program [28]. It should be assumed (V. V. Revo, 1986–2018) that the attribute element for disease programs at all levels of the systemic organization of life are complexes of protein nature and their wave forms. S. P. Botkin, I. V. Davydovsky [12], H. Selye recognized the programm mechanism of the diseases [57]. Davydovsky emphasized in this connection that “whatever the characteristic of the pathological process (traumatic, infectious, cancerous) it is a self-developing process, independent of whether the etiological factor is involved (microbe or infection) or not (the instrument that caused the injury, the carcinogen that caused the cancer)". There are two forms of diseases: acute and chronic. The pathogenesis of these forms is of a different nature. In one variant the acute disease may cease, and the chronic disease to enter into a remission phase. Such an outcome is possible with the effective work of adaptation mechanisms, e.g., immunity in the course of an infectious process, or with effective treatment. Another option involves death due to the destruction of vital organs. The work of the positive feedback mechanism accelerates depletion of adaptation resources. The situation is complicated by polymorbidity (syn. comorbidity) – the simultaneous development of several chronic diseases of one or another syntropic cluster. Manifestations of the disease in the wild distinguishes a living being among others in the general system of the food chain. Therefore, polymorbidity in the wild is extremely rare. The problem of eliminating diseases has no solution, because any of them is a natural phenomenon immanent for the living beings. Sometimes a disease can even be beneficial for the body, because it increases diversity, and this reduces entropy [31]. Programs of any disease are available for management, with the exception of socialoses (syn. Social diseases). Socialoses not available for formalization, even in the first approximation because of their transcendental nature. However, appropriate alternatives make it possible to effectively manage even socialoses, although only at a phenomenological level [37]. So, B. Franklin proposed (1752) a lightning conductor, which did not cancel the natural process – a thunderstorm and its dangerous manifestation in the form of lightning, but became an effective alternative, eliminating the danger of electric shock. Compare with Illness. Look Postulates № 2 and № 21 in the second part of the book.
Illness – is a general definition of processes in a living being, for example, syndromes and symptom complexes, which reduce its adaptive capabilities and do not have innate programs of their own development (V. Revo).
© Valeriy Revo 2019
Laboratory of Disease Program Management Technologies™
Selected fragments of the 4th edition of the book of MD, PhD, Professor V. Revo "Prolegomena to Future Metamedicine." Part I. 2019.
Disease, syn. Nosological form – is the definition of the phenomenon of unfolding in the body of a phylogenetically determined innate specific program process, which reduce the adaptive capabilities of a living being. However, today the disease is presented as "… any harmful deviation from the normal structural or functional state of the body, usually associated with certain signs and symptoms and differing in nature from physical damage" [62]. The epithet "harmful" is not correct in this context, because in the body we have various forms of harmfulness, e.g., many metabolic products. The World Health Organization defines the disease as "a violation of the function or structure of any part of the body" due to the inability to fully adapt to "stimuli and stresses." It is assumed that the disease "can be prevented or treated by changing any combination of factors" [63]. These declarations illustrate the archaic nature-philosophical approach to the disease, which cannot offer technologies for the prevention of non-communicable diseases by definition. The systemic information paradigm (V. Revo, 1986) represents the disease as a phased development in the organism of any particular phylogenetically conditioned congenital program [28]. It should be assumed (V. V. Revo, 1986–2018) that the attribute element for disease programs at all levels of the systemic organization of life are complexes of protein nature and their wave forms. S. P. Botkin, I. V. Davydovsky [12], H. Selye recognized the programm mechanism of the diseases [57]. Davydovsky emphasized in this connection that “whatever the characteristic of the pathological process (traumatic, infectious, cancerous) it is a self-developing process, independent of whether the etiological factor is involved (microbe or infection) or not (the instrument that caused the injury, the carcinogen that caused the cancer)". There are two forms of diseases: acute and chronic. The pathogenesis of these forms is of a different nature. In one variant the acute disease may cease, and the chronic disease to enter into a remission phase. Such an outcome is possible with the effective work of adaptation mechanisms, e.g., immunity in the course of an infectious process, or with effective treatment. Another option involves death due to the destruction of vital organs. The work of the positive feedback mechanism accelerates depletion of adaptation resources. The situation is complicated by polymorbidity (syn. comorbidity) – the simultaneous development of several chronic diseases of one or another syntropic cluster. Manifestations of the disease in the wild distinguishes a living being among others in the general system of the food chain. Therefore, polymorbidity in the wild is extremely rare. The problem of eliminating diseases has no solution, because any of them is a natural phenomenon immanent for the living beings. Sometimes a disease can even be beneficial for the body, because it increases diversity, and this reduces entropy [31]. Programs of any disease are available for management, with the exception of socialoses (syn. Social diseases). Socialoses not available for formalization, even in the first approximation because of their transcendental nature. However, appropriate alternatives make it possible to effectively manage even socialoses, although only at a phenomenological level [37]. So, B. Franklin proposed (1752) a lightning conductor, which did not cancel the natural process – a thunderstorm and its dangerous manifestation in the form of lightning, but became an effective alternative, eliminating the danger of electric shock. Compare with Illness. Look Postulates № 2 and № 21 in the second part of the book.
Illness – is a general definition of processes in a living being, for example, syndromes and symptom complexes, which reduce its adaptive capabilities and do not have innate programs of their own development (V. Revo).
© Valeriy Revo 2019